Stress Reset
Stress Reset
Stress Reset
Stress Reset
Ingredients
4.6
Rated 4.6 out of 5 stars
4.6 Stars (715 Reviews)

Stress Reset

Confidence

Balance

Stress Reset is designed to maintain healthy cortisol levels and optimize neurotransmitter activity—the critical processes that keep your mind calm and resilient.

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Ingredients

• Withania Somnifera (Ashwagandha), 120mg

• Crocus sativus (Saffron), 28mg

• Zembrin (Sceletium tortuosum), 25mg

• Rhodiola Rosea (Fermented Salidrosides), 30mg

• Magnesium Bisglycinate, 84mg

• Dihydrohonokiol-B (Honokiol extract), 10mg


Capsules with caffeine contain:

• Caffeine Anhydrous, 100mg

• Camellia siensis (L-Theanine), 100mg

How To Use

Suggested Use: Adults, take two (2) capsules daily. Adjust to 1-3 capsules, depending on sensitivity or as recommended by your healthcare provider.


CAUTION: Always consult your healthcare professional before use, especially if you have a medical condition or are taking medication. Do not use if you are pregnant or nursing. Keep out of reach of children.
After 30 Days

Stress Reset has helped hundreds of thousands of customers focus—and follow through.

Don't just take our word for it. See for yourself what Thesis customers experience within 30 days of taking Stress Reset.

83%

of people reported reduced stress levels*

83%

of people reported feeling more relaxed and calm*

Results from real customers* within

30 Days

Improvement in mood 77%
Ability to handle daily stressors 77%
More emotionally resilient 73%

*Results are from an open-label consumer perception study conducted in November 2025 that included 30 customers who were taking Thesis for at least 30 days. Customers who completed the study received $10 in store credit for sharing their feedback about Stress Reset.

Clinically-proven, powerhouse ingredients for game-changing benefits.

Withania Somnifera (Ashwagandha)
Key Function
Promotes stress relief

Withania Somnifera (Ashwagandha)

Promotes stress relief

Withania Somnifera (Ashwagandha)

What is it?

Ashwagandha, also known as “Indian Ginseng” or “Indian Winter Cherry,” is a powerful adaptogenic herb deeply rooted in Ayurvedic medicine. Traditionally used for stress relief, cognitive function, and overall vitality, it helps the body adapt to physical and mental stressors while promoting energy balance, emotional well-being, and resilience.

Stress Reset Dosage

120mg

Other Nootropics

31–250mg on average

The Science

By utilizing both roots and leaves (other Ashwagandhas use the roots only), Ashwagandha maximizes its phytochemical diversity, providing a richer spectrum of bioactives, including unique withanolides, polyphenols, and flavonoids, enhancing its stress-modulating, sleep-supporting, and immune-boosting properties. This innovative approach also promotes sustainability, reducing plant waste and pollution while delivering clinically backed benefits for mental clarity, energy balance, emotional well-being, and restorative sleep. Shoden® sets a new standard for potency, efficacy, and eco-conscious innovation in adaptogenic supplements.
Crocus sativus (Saffron)
Key Function
Enhances mood

Crocus sativus (Saffron)

Enhances mood

Crocus sativus (Saffron)

What is it?

Known as the “Golden Spice,” saffron has long been celebrated for its ability to support emotional well-being and help the body cope with occasional stress. Our premium saffron extract harnesses the potent bioactive compounds crocins and safranals—standardized to 7.5% and 1% respectively—to promote a positive mood, mental clarity, and relaxation.

Stress Reset Dosage

28mg

Other Nootropics

28-30mg

The Science

By delivering a concentrated dose of these naturally occurring actives, this specialized extract offers a powerful, targeted approach to stress management, making it an essential cornerstone of our Stress Reset formula.
Sceletium Tortuosum (Kanna)
Key Function
Reduces occasional anxiety

Sceletium Tortuosum (Kanna)

Reduces occasional anxiety

Sceletium Tortuosum (Kanna)

What is it?

Sceletium tortuosum, commonly known as kanna, has been traditionally used by the San and Khoikhoi tribes of South Africa for centuries to promote well-being, reduce stress, and enhance endurance. Historically, it was chewed, smoked, or brewed as a tea for mood enhancement, relaxation, and cognitive clarity.

Stress Reset Dosage

25mg

Other Nootropics

25mg

The Science

Zembrin® is a clinically studied, standardized extract with a patented alkaloid profile, ensuring ≥ 60% mesembrenone + mesembrenol, ≤ 20% mesembrine, and ≥ 5% mesembranol. This unique composition optimizes mood support, cognitive performance, and stress regulation while minimizing sedation​.
Rhodiola Rosea (Fermented Salidroside)
Key Function
Supports neurotransmitter balance

Rhodiola Rosea (Fermented Salidroside)

Supports neurotransmitter balance

Rhodiola Rosea (Fermented Salidroside)

What is it?

Salidroside is a bioactive tyrosol glycoside found in Rhodiola rosea, an adaptogenic plant traditionally used to support resilience to physical and mental stress. Our formula features a highly purified form of salidroside produced through precision fermentation—ensuring a sustainable and stable alternative to wild-harvested rhodiola.

Stress Reset Dosage

30mg

Other Nootropics

10–20mg on average

The Science

Salidroside has been studied for its role in modulating the hypothalamic-pituitary-adrenal (HPA) axis, supporting cellular adaptation to stress. It has also been shown to influence mitochondrial function, antioxidant pathways, and key neurotransmitters such as serotonin, dopamine, and norepinephrine, which are involved in mood, cognitive function, and overall mental performance. The precision fermentation process enhances bioavailability, optimizing absorption for effective support of the body's natural stress response and energy metabolism.
Magnesium Bisglycinate
Key Function
Promotes a sense of calm

Magnesium Bisglycinate

Promotes a sense of calm

Magnesium Bisglycinate

What is it?

Our formula includes 600 mg of magnesium bisglycinate, delivering 84 mg of pure, absorbable magnesium. This highly bioavailable form is paired with glycine, an amino acid that enhances absorption and is gentle on digestion.

Stress Reset Dosage

84mg

Other Nootropics

10–100mg on average

The Science

Magnesium is essential for relaxation, stress support, and overall well-being—it helps regulate the nervous system, supports muscle relaxation, and plays a key role in energy production. By using magnesium bisglycinate in our Stress Reset formula, we ensure your body gets the benefits of magnesium without the digestive discomfort some other forms can cause, helping you unwind and recharge.
Dihydrohonokiol-B (Honokiol extract)
Key Function
Supports GABAergic activity

Dihydrohonokiol-B (Honokiol extract)

Supports GABAergic activity

Dihydrohonokiol-B (Honokiol extract)

What is it?

Our formula features Dihydrohonokiol-B (DHH-B), a naturally derived compound found in magnolia bark. DHH-B has been studied for its interaction with GABA receptors, which play a key role in the body's natural stress response. By supporting GABAergic activity, DHH-B may help promote a sense of calm and relaxation during occasional stress. This ingredient is included in our Stress Reset formula to help support a balanced mood and maintain mental clarity without drowsiness.

Stress Reset Dosage

10mg

Other Nootropics

7.5-10mg on average

The Science

Preclinical research confirms that Dihydrohonokiol-B (DHH-B), a compound derived from magnolia bark, may help promote calm behavior in animals under stress. In behavioral studies, mice given DHH-B spent more time in open spaces and displayed reduced stress-related avoidance—effects similar to those seen with low-dose diazepam. Biochemical tests showed that DHH-B supports GABA receptor activity, a key pathway in the body’s natural stress response. These findings suggest that DHH-B may help support relaxation and emotional balance by modulating GABA signaling.
Camellia sinensis (L-Theanine)
Key Function
Reduces jitters

Camellia sinensis (L-Theanine)

Reduces jitters

Camellia sinensis (L-Theanine)

What is it?

L-Theanine is a naturally occurring amino acid found in tea leaves, known for its ability to promote relaxation without sedation. It works by promoting alpha brain wave activity, a pattern associated with calm focus and mental clarity.

Stress Reset Dosage

100mg

The Science

Research shows that L-Theanine supports cognitive function by improving reaction time, attention, and stress resilience. It also supports neurotransmitters like GABA and dopamine, which play key roles in mood and mental performance. Unlike traditional calming agents, L-Theanine reduces occasional stress while maintaining alertness, making it a powerful ingredient for supporting focus, relaxation, and cognitive balance.
Caffeine Anhydrous
Key Function
Promotes focus and energy

Caffeine Anhydrous

Promotes focus and energy

Caffeine Anhydrous

What is it?

Caffeine is a naturally occurring stimulant found in coffee, tea, and other plant sources, known for its ability to enhance alertness and mental energy. It works by blocking adenosine, a neurotransmitter that promotes relaxation, leading to increased wakefulness and focus.

Stress Reset Dosage

100mg

The Science

Research shows that caffeine supports cognitive function by improving reaction time, attention, and processing speed, making it a key ingredient for mental performance. It also helps support dopamine and norepinephrine production, neurotransmitters that contribute to motivation and mood. Unlike other stimulants, caffeine provides a fast-acting boost in energy and concentration, making it a powerful tool for enhancing focus and productivity.
  • quality guaranteed
  • third-party tested
  • no unnecessary fillers
  • non-gmo
  • game-changing results

Find more clarity, motivation, and stability over time.

Person holding a product
Week 1

Feel more grounded, fast

L-Theanine and Zembrin® promote calm focus and balance—so you can feel less reactive, faster.*

Month 1

​​More calm, more clarity

Ashwagandha, Magnesium, and Saffron support cortisol balance, mood, and focus—making daily stress easier to manage.*

Month 3

Respond, don’t react

Zembrin®, salidroside, and DHH-B promote stress resilience, emotional steadiness, and clear, calm energy all day.*

Month 6

Build true stress resilience

Ashwagandha, salidroside, and Vitamin D support emotional balance, mental clarity, and lasting calm energy, even when life feels chaotic.*

*Results may vary

Driven by science. Rigorously validated.

"It has completely changed my focus and motivation"
"I feel like nothing can get in my way"
"The boost I need for my productivity"
"I’m more capable of handling a really chaotic world"
"I start every day off with Thesis"

We’re obsessed with perfecting powerful nootropics.

Thesis is pioneering a new wave of nootropics through data-driven formulations, iterative testing, and a relentless commitment to results.

We analyze all of our formulas for microorganisms including bacteria, viruses, and fungi.

We verify that every formula contains the exact amounts of active ingredients listed on the label.

We screen each batch for harmful heavy metals like lead, arsenic, cadmium, and mercury.

We test raw materials to ensure they’re free from pesticide residues, even trace amounts.

Guaranteed results, or your money back

All Thesis products come with a money back guarantee. If you don't feel 50% improvement in your cognitive focus area within 30 days, we'll refund you for your entire purchase.

Reviews

Reviews reflect the individual experiences and opinions of the customers who wrote them, not those of Thesis. We do not verify or endorse any claims made in customer reviews, and individual results may vary. Read our full reviews disclaimer

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